In addition, ZFAS1 is significantly associated with certain clinicopathological features in different human tumors, such as lymph node metastasis, TNM stage, and tumor size.[10,12–14] However, due to the limited sample size and single center design of the present studies, a systematic review of literature was performed to evaluate and predict the overall risk of high ZFAS1 expression for the survival prognosis and clinicopathological features of patients with various types of cancer. This evidence concerns the gene ZFAS1 and cancer.