Recognizable epilepsy syndromes comprised the known spectrum of GRIN2A-associated epilepsy syndromes, such as benign epilepsy with centrotemporal spikes, atypical childhood epilepsy with centrotemporal spikes and Landau-Kleffner syndrome. The gene discussed is GRIN2A; the disease is developmental and/or epileptic encephalopathy with spike-wave activation in sleep.