For CFT073 infection, the incidence of chronic cystitis at 28 dpi was higher in the single depletion groups (67% for CD4-depleted and 62% for CD8-depleted, compared to 46% in isotype-treated mice, S7A and S7B Fig), but the difference was not statistically significant, and similar proportions of mice cleared the infection after seven days (S7C Fig). This evidence concerns the gene CD4 and chronic cystitis.