TNF and infection: Cytokines with increased mRNA accumulation at all time points includedIl10 andIl21, whereas for others (e.g.Il1b andIl6) there was progressive increase in mRNA accumulation over time.Ifnγ mRNA abundance also increased over time post infection, whilst enhanced accumulation ofTnf mRNA was observed only late in infection and other TNF superfamily members showed variable responses.