CXCL16 and neoplasm: To confirm a role of CXCL16 in driving GAMs toward a pro-tumor phenotype in vivo, we implanted GL261 cells into the brain of wt and cxcr6ko mice and, after 17 days, CD11b+ cells were isolated from the ipsi- and contra-lateral brain hemispheres of each mice and analyzed by RT-qPCR.