Mice injected with tumor cells silenced for CXCR6 revealed a significant reduction (67%) in tumor volume compared to mice injected with GL261 expressing CXCR6 (2.19 ± 0.47 mm3 shCXCR6 + IPTG mice vs. 6.54 ± 1.26 mm3 shCXCR6–IPTG) (n = 5, p < 0.05; Student's t-test). This evidence concerns the gene CXCR6 and neoplasm.