To exclude that differences observed in vivo between tumor volume in GL261 and shCXCL16-GL261 bearing mice might be due to clonal differences between cells rather than to the CXCL16 silencing, we checked for the expression of markers involved in tumor immune recognition (specifically MHC class I, CD1 and PD-L1) as well as tumor cell migration and invasion (CD44). Here, CD44 is linked to neoplasm.