In addition (Figure 5E) we found that mice injected with tumor cells silenced for CXCL16 presented a reduced number of glioma cells that migrate and invade the surrounding brain tissue (12.16 ± 0.82 cells for brain slice) compared to mice injected with GL261 (24.85 ± 1.49 cells for brain slice) (n = 3, p < 0.05; Student's t-test). Here, CXCL16 is linked to central nervous system cancer.