CXCR6 and central nervous system cancer: Moreover, as reported in Figure 4H, in mice injected with tumor cells silenced for CXCR6 there was a reduced number of glioma cells that migrate and invade the surrounding brain tissue (15.00 ± 1.8 cells for brain slice) compared to mice injected with cells not silenced (28.6 ± 3.9 cells for brain slice) (n = 3–4, p < 0.05; Student's t-test).