The results of this study revealed that in a homogeneous sample of middle-aged Caucasian (Croatian origin) veterans with combat related PTSD: (1) BDNF Val66Met and BDNF C270T polymorphisms were not significantly associated with BMI or plasma lipid levels; (2) the presence of one or two T alleles of BDNF C270T polymorphism was related to slightly (nominally) higher HDL cholesterol values; but this association disappeared after controlling for the influence of age. Here, BDNF is linked to post-traumatic stress disorder.