IL19 and Stroke: For example, elevations in the expression of mRNA encoding IL-19 have been noted in peripheral blood mononuclear cells in an animal model of stroke (Rodriguez-Mercado et al., 2012), and IL-19 administration prior to ischemia-reperfusion injury has been associated with decreased leukocyte activation/infiltration and lessened neurological damage (Xie et al., 2016).