Within the CNS, inhibition of IL-20 using a neutralizing antibody has been shown to limit the inflammatory damage associated with acute ischemic brain injury (Chen and Chang, 2009), and IL-20 exposure has been demonstrated to promote the release of the potent chemoattractants MCP-1 and IL-8 by a glioblastoma cell line (Chen and Chang, 2009). Here, IL20 is linked to glioblastoma.