The CGGA and TCGA databases of glioma revealed that the mRNA levels of Fstl1 were higher in high-grade glioma (HGG) than non-tumor brain tissue (NBT) (Supplementary Fig.1A and B), and the study of clinical samples confirmed the above results (Fig.1a and b, Supplementary Fig. 1C). The gene discussed is FSTL1; the disease is glioma.