At 2-day post-infection, T cell numbers (CD4+ and CD8+) in spleen (Fig. 3g) and B cells in addition to CD4 + T cells in the liver (Fig. S3G were increased in Batf2−/− mice, whereas myeloid cell populations such as macrophages, dendritic cells, and neutrophils remain unaffected in the spleen (Fig. 3h). Here, CD4 is linked to infection.