The genotypes (i.e., rs2074192 (CC), rs2285666 (TT+CT), and rs4646142(CC+CG)) related to high atherosclerosis (CAS ≥ 50%) risk were not associated withhigh levels of RAAS (see Table 6 andSupplementary Table 8), and the genotypes(i.e., rs42040157 (CC+CT), rs4646155 (TT+CT), and rs4830542 (CC+CT)) associated withLAE were associated with high levels of RAAS (see Table 6), suggesting that ACE2 genetic variants have the potential toaffect circulating RAAS activation. Here, ACE2 is linked to atherosclerosis.