BCL11A and acne: Enrichment (FDR < 0.05) of 15 gene-sets was observed, including gene-sets relating to branches of the mammalian phenotype ontology tree that describe abnormal epidermal and ectodermal development (Supplementary Table 6); these implicate candidate causal genes with related biological functions at otherwise unresolved acne risk loci, including BCL11A at 2p16.1 and GLI2 at 2q14.2 (Table 1, Supplementary Table 6).