Other ion-transporters, like the KCC4 K–Cl cotransporter SLC12A6 (p = 0.026, log2FC = − 0.67) and the organic anion clearance transporter SLCO4A1 (p = 0.0001, log2FC = − 1.85), were upregulated in AD. The gene discussed is SLC12A6; the disease is Alzheimer disease.