AVP and acute coronary syndrome: These include troponin-only strategies optimizing the ESC standard algorithm for the diagnosis of NSTEMI (0 h/1 h, 0 h/2 h and 0 h algorithms), strategies combining troponin measurement with clinical data (Manchester Acute Coronary Syndromes decision rule, heart score) and dual-marker strategies combining troponin with other biomarkers (e.g., copeptin and Heart-type fatty acid-binding protein).