In addition, upregulation of some transcripts in ALS could reflect compensatory mechanisms preventing axon damage or dysfunction in SOD1G93A axons, including Dhx36 (Bicker et al., 2013), the ALS-causative gene Nek1 (Kenna et al., 2016), F3 (Bizzoca et al., 2009), Rbpms (Hornberg et al., 2013), and Farp1 (Zhuang et al., 2009) (Figure 5E). Here, FARP1 is linked to amyotrophic lateral sclerosis.