SHANK2 and cancer: Sugahara also listed several other genes in 11q13.3 that are related to cancer development, namely TPCN2, MYEOV, CCND1, ORAOV1, TMEM16A, FADD, PPFIA1, CTTN, SHANK2, and DHCR7. We also assessed their status by using the P score analysis; the genes are indicated in blue in Fig 8.