HTR1A and anxiety disorder: A recent paper from Baas and Heitland (2015) suggests that a 5-HT1A receptor polymorphism (rs6295) is associated with enhanced contextual anxiety, which further supports a role for human 5-HT1A receptors in anxiety disorders and is in line with pre-clinical studies showing that 5-HT1A receptor deletion enhanced the fear response to contextual cues in mice (Klemenhagen et al. 2006).