NFKB1 and vascular dementia: Liu et al. indicated that GJ extracts could improve learning and memory abilities of ischemia-induced vascular dementia rats/mice, and its mechanism may be related to the promotion of NT-3 and brain derived neurotrophic factor (BDNF) expression, reduction of NF-κB expression, inhibition of the release of inflammatory factors, and the neurons apoptosis [26, 27].