BCR and myeloproliferative disorder: Though 35.6% (21 out of 59) of the ASE genes were common in both normal and cancer tissues, it was reported that the change in the allele ratio of the ASE can also lead to phenotypic diversity, for example, a study reported that the proportion of the JAK2 V617F mutant allele in RNA levels is significantly associated with distinct subtypes of BCR/ABL-negative myeloproliferative neoplasms (MPNs) (Kim H.R. et al., 2013).