In triple-negative breast cancer cells, it was further shown that the β1,3-N-acetylglucosaminyl transferase (B3GNT3), involved in the biosynthesis of poly-N-acetyllactosamine chains, is important for the interaction between PD-1 and its ligand PD-L1 (94). The gene discussed is PDCD1; the disease is triple-negative breast carcinoma.