Anatomic T1-weighted/T2-weighted and dynamic-contrast enhancement (DCE) MRI analysis indicated a significant increase in post-gadolinium enhancement, tumor vascularity through quantification of plasma volume (Vp) as well as vessel permeability through calculation of the contrast transfer coefficient (Ktrans) in NDRG1-overexpressing tumors as compared to mock tumors (Fig. 6g and Supplementary Table 4). The gene discussed is NDRG1; the disease is neoplasm.