DNAJC5 and malaria: The most advanced vaccine, RTS,S/AS01, includes a recombinant malarial protein (circumsporozoite protein [CSP]) and provides partial protection against clinical malaria in children (vaccine efficacy [VE], 36.3%; 95% confidence interval [CI], 31.8% to 40.5%) and in young infants (VE, 25.9%, 95% CI, 19.9% to 31.5%) (2).