In addition the evidence of a recent report that demonstrated that M(Tc-8w) macrophages which arises from the late stages of infection in the cysticercosis model by T. crassiceps are mostly PD-L2+ and do not express IL-10 [44] showed that in this infection, presence of IL-10 is not an alternative activation determinant, but membrane markers as PD-Ls and the diminished expression of pro-inflammatory cytokines markers are more relevant [37]. The gene discussed is PDCD1LG2; the disease is cysticercosis.