AGTR1 and ductal breast carcinoma in situ: Similarly, an MTT assay also revealed that fluvastatin preferentially inhibited the cell proliferation of MCF10.AT1 cells as indicated by an IC50 of 2.1 μM in MCF10.AT1 cells relative to half maximal inhibitory concentration (IC50) of 18 μM in MCF10.DCIS cells (p < 0.01), values that are derived from the fluvastatin dose response curves shown in Fig. 4c.