Similarly, ki-67 staining indicated that miR-140-3p-1 restoration modestly inhibited the cell proliferation (by 9.8%, p = 0.08) of preneoplastic MCF10.AT1 cells but not in MCF10.DCIS cells (Additional file 2: Figure S1). The gene discussed is MKI67; the disease is ductal breast carcinoma in situ.