MTA1 is a component of several chromatin remodeling complexes, including the nucleosome remodeling and deacetylation complex.65, 66, 67 Previous studies revealed that MTA1 is one of the most upregulated proteins in human cancer, and it is associated with cancer progression, aggressive phenotypes, and poor prognosis in patients with cancer.26, 67 In the present study, both DcR3 and MTA1 were overexpressed in OSCC patients (Figures 2 and 5), and MTA1 was positive correlated with DcR3 expression in the clinical data (Figure 5A). The gene discussed is MTA1; the disease is cancer.