INS and type 1 diabetes mellitus: At baseline BP, neither T1DM (0.04 ± 0.01 ml/min/gkw) nor T1DM+insulin (0.08 ± 0.01 ml/min/gkw) affected CLi (control, 0.08 ± 0.01 ml/min/gkw), while increasing BP led to a similar significant increase in CLi in all three groups (Fig. 4C; P < 0.01).