CD4 and colorectal carcinoma: GATA3 has been described as a master regulator of T‐helper 2 cell differentiation in mature CD4 (+) T cells and has been associated with T cell development.79 One possible explanation of the functional impact is that processed meat could trigger a pro‐tumorigenic inflammatory or immunological response,55, 80 and loss of GATA genes or silencing of expression can increase CRC risk.81