HIATL1 is a member of the solute carrier group of membrane transport, which makes the move of substances (such as peptides, amino acids, proteins, metals, and neurotransmitters) directly into or out of cells possible.82, 83 Gene expression analyses indicate that the variants at 9q22.32/HIATL1 that interact with alcohol on CRC risk through genome‐wide G×E interaction analyses can also impact HIATL1 expression,60 which suggests that alcohol may modify the effects of HIATL1 on CRC risk through its influence on HIATL1 expression levels.60 This evidence concerns the gene SLC71A2 and colorectal carcinoma.