H19 promotes tongue squamous cell carcinoma invasion through β‐catenin/GSK3β/EMT signaling via association with EZH2.25 Accumulating evidence highlighted that aberrant expression of H19 was closely related to embryogenesis, fetal growth, and tumorigenesis.26 Proper development of human placenta is essential for the maintenance of normal pregnancy. The gene discussed is GSK3B; the disease is tongue squamous cell carcinoma.