For example, latent membrane protein 1 (LAMP1) is highly expressed in exosomes released from nasopharyngeal cancer (NPC)-derived malignant epithelial cells.55 Similarly, a specific cell surface proteoglycan, glypican-1 (GPC1), was detected in exosomes from pancreatic cancer.56 Collectively, to maintain the specificity of exosomes derived from different donors, various protein cargos must be sorted into exosomes before their release. Here, GPC1 is linked to pancreatic neoplasm.