GPC1 and familial pancreatic carcinoma: For example, latent membrane protein 1 (LAMP1) is highly expressed in exosomes released from nasopharyngeal cancer (NPC)-derived malignant epithelial cells.55 Similarly, a specific cell surface proteoglycan, glypican-1 (GPC1), was detected in exosomes from pancreatic cancer.56 Collectively, to maintain the specificity of exosomes derived from different donors, various protein cargos must be sorted into exosomes before their release.