CHD4 and autism: For example, mutations in CHD4 (OMIM # 617159) cause neurodevelopmental delays, chromatin remodelers have been associated with cognition (Wenderski and Maze, 2016), Eif4e has been tightly linked with autism (St Clair and Johnstone, 2018) and autophagy with autism, brain degeneration and schizophrenia (Sragovich et al., 2017).