TNFSF10 and neoplasm: These results showed that high expression of IL12A and IL12B in these pathways is beneficial to resisting C. perfringens type C. TNFSF10 (TRAIL) can be expressed in different immune cells (such as NK cell, T cell, and macrophage cell) and plays an important role in immune modulation, pathogen resistance, and tumor surveillance (Ikeda et al., 2010; Jin & El-Deiry, 2006).