TNF and early-onset autosomal dominant Alzheimer disease: KEGG pathway analysis of trans-target genes of lncRNAs demonstrated that SR and SS shared some pathways related to immune system function, such as the TNF signaling pathway, NF-kappa B signaling pathway, B cell receptor signaling pathway, MAPK signaling pathway, Alzheimer’s disease, and Huntington’s disease (Tables S8-4 and S8-5, corrected P < 0.05).