Mnk1/2-/- and Eif4eki/ki mice displayed increased immobility in the force-swimming and tail suspension tests, increased latency to feed in a novelty suppressed feeding assay, and anxiety behaviors in the open-field and elevated plus maze tests (Aguilar-Valles et al., 2018; Amorim et al., 2018). The gene discussed is MKNK1; the disease is Anxiety.