HSPB1 in subnetwork 6, EPHX1 in subnetwork 8, and TPM2 in subnetwork 9 were indicated to have potentially functional relationships with diseases such as neuronopathy distal hereditary motor, Charcot-Marie-Tooth disease axonal, hypercholanemia familial, preeclampsia/eclampsia 1, and arthrogryposis distal. The gene discussed is HSPB1; the disease is arthrogryposis.