Whilst many studies are still underway, only one recent clinical study analyzing the effect of the liraglutide analog in regards to Alzheimer's disease has been reported (NCT01469351) (275), and two clinical trials and one population based nested case-control study assessing Parkinson's Disease and GLP-1R activity (NCT01971242, NCT01174810) (28, 267, 276–278). Here, GLP1R is linked to early-onset autosomal dominant Alzheimer disease.