Netrin-1 also has a number of non-neuronal functions: regulating angiogenesis (Lu et al., 2004; Park et al., 2004; Wilson et al., 2006; Larrivee et al., 2007), inflammation (Tadagavadi et al., 2010; Boneschansker et al., 2016), and tumor progression (Mehlen et al., 2011). This evidence concerns the gene NTN1 and neoplasm.