It was also shown that either repeated administrations of Ser or Lv-TSPO injection increased the number of transitions (P = 0.0018 for Lv-NC+Ser+FS vs. Lv-NC+FS; P = 0.0461 for Lv-TSPO+FS vs. Lv-NC+FS; Figure 1E), suggesting that TSPO overexpression in DG of hippocampus significantly ameliorated PTSD-associated anxiogenic-like behaviors. The gene discussed is TSPO; the disease is post-traumatic stress disorder.