TSPO and post-traumatic stress disorder: It was further showed that these above anti-PTSD behavioral effects of TSPO overexpression was reversed by PK11195 administration (P = 0.0412 for freezing time in contextual freezing test, Figure 1D; P = 0.0486 for dark-to-light transition in light–dark transition test, Figure 1E; P = 0.0355 for the percentage of entries into open arms, P = 0.0432 for percentage of time spent in open arms in EPM test, Figures 1H,I).