STAT6 and Herpesviridae infectious disease: Regarding the role of STAT6 signaling in herpesvirus infection and mediated pathogenesis, it has been reported that STAT6 can be induced to translocate into the nucleus and activate the immune response by primary infection of herpes simplex virus 1 (HSV-1) or Herpesvirus saimiri (a T-lymphotropic monkey herpesvirus) in different cell types[4,31].