One such example is provided in Fig. 9, where we show that in tumor, there is a high degree of co-expression between poly(ADP-ribose) polymerase-2 (PARP2) and 10 cell cycle genes (Fig. 9a) selected from MSigDB “REACTOME_CELL_CYCLE” gene set [34, 35], whereas this co-expression is diminished in normal tissues (Fig. 9b). This evidence concerns the gene PARP2 and neoplasm.