STX1B and juvenile myoclonic epilepsy: Our analyses implicate STX1B as a potential gene underlying the association of JME at the 16p11.2 locus and the top variant in the locus is an eQTL that strongly correlates with expression of STX1B in the dorsolateral prefrontal cortex (Spearman’s correlation: Rho = 0.33, p = 3 × 10−14)23.