KCNIP2 and genetic generalized epilepsy: Using this approach, we found a novel genome-wide significant locus at 10q24.32 in all epilepsy (MTAG p = 2.2 × 10-8) and genetic generalized epilepsy (MTAG p = 4.0 × 10-8) which encompasses the Kv-channel-interacting protein 2 (KCNIP2) gene (Supplementary Fig. 14), loss of which is associated with seizure susceptibility in mice47.