Analyzing the RNA-seq dataset from GSE50760 which containing 18 normal colonic epithelium, 18 primary colorectal cancers, and 18 metastasized cancers in liver, we noted that lncRNA B3GALT5-AS1 (C21orf88) is reduced in primary colorectal cancers compared with normal colonic epithelium and is further reduced in metastasized cancers in liver (Fig. 1A). This evidence concerns the gene B3GALT5 and cancer.