As to colon cancer, several lncRNAs are revealed to regulate colon cancer cells proliferation, apoptosis, migration, invasion, chemoresistance, and so on, such as lncRNA N-BLR, GAS5, HNF1A-AS1, CRNDE, LINC01133 [28–32]. Here, HNF1A is linked to malignant colon neoplasm.