BDNF and brain infarction: Brain injury: The pooled effect estimate favored HDACi treatment over controls for the outcomes brain infarct size (SMD −1.70, 95% CI −2.22 to −1.18, p < 0.0001, 19 studies), brain lesion volume (SMD −1.13, 95% CI −1.81 to −0.45, p = 0.001, 7 studies), time on rotarod (SMD 1.15, 95% CI 0.25–2.06, p = 0.013, 7 studies), BDNF levels (SMD 2.38, 95% CI 0.88–3.88, p = 0.002, 4 studies), and glial fibrillary acidic protein (GFAP) (SMD −1.93, 95% CI −2.81 to −1.05, p < 0.0001, 4 comparisons) when compared with untreated animals.