Previous studies have reported the association of variants near CBLN2, and PDE1A and DNAJC10 with pulmonary arterial hypertension.7, 8 These common variant signals showed no association with pulmonary arterial hypertension in the combined NIHRBR, PAHB, and BHFPAH cohorts (p=0·17 for CBLN2 and p=0·24 for PDE1A and DNAJC10; appendix p 14). The gene discussed is PDE1A; the disease is pulmonary arterial hypertension.