Using an ‘aneuploidy score’ for each tumor based on the total number of arm-length alterations (Taylor et al., 2018), we verified that TP53-mutant tumors exhibit more aneuploidy than TP53-wild-type tumors (Figure 3—figure supplement 1A), and that total aneuploidy is a poor prognosis factor in several cancer types (Figure 3—figure supplement 1C). Here, TP53 is linked to neoplasm.