We then examined the tumor growth and luciferase expression in C57BL/6 mice receiving HDI with the plasmids pKT2/CLP-AKT-OVA-HBc-HBs-LUC, pT/Caggs-NRASV12, and pCMV(CAT)T7-SB100 and found two different patterns of tumor growth in the injected mice. Here, KRT88P is linked to neoplasm.