As relevant findings, we show that the SNP variants analyzed, located in the promoter regions of the IL-10 gene: -592 (A/C) and − 819 (T/C), as well as for the IL-4: -590 (C/T) and IL-4Rα (Q576R and Ile50Val), did not present differentially in gastric cancer patients with respect to the group of healthy individuals; even for the last two variants mentioned, homozygous genotypes for the mutation were not evident, so that, at least in the population analyzed, no evidence was noted of any relationship between the presence of these polymorphisms and the development of gastric carcinoma. The gene discussed is IL4; the disease is gastric cancer.