In that sense, a recent study in the Chinese province of Liaoning reveals, for example, association between the presence of mutation for SNP -819 (C/T) consistent with an ATC haplotype (− 1082/− 819/− 592) and greater risk of having gastric cancer (OR = 3.21; P = 0.015) [44], to which Wang et al. [45] add the registry of association among the three SNPs in promoter region of the IL-10 gene, evaluated in our study, and gastric cancer, especially in Asian population, in contrast with that determined for our population. This evidence concerns the gene IL10 and gastric cancer.