KCNQ1OT1 and Arrhythmia: Long non‐coding RNA is a type of RNA with a length of >200 nucleotides and non‐coding protein.122 In recent years, many reports have focused on the association of lncRNA with pyroptosis in CVDs, such as maternally expressed gene 3 (MEG3)6 and metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1).17 The KCNQ1 opposite strand/anti‐sense transcript 1 (Kcnq1ot1) is a lncRNA located in human chromosome 11p15.5.123 Kcnq1ot1 is involved in various CVDs, including acute myocardial damage124 and arrhythmia.125 Silencing Kcnq1ot1 ameliorates cardiac function and fibrosis in diabetic mice.