Less ROS was observed in the MAPK15-expressing NPC cells than in the vector control at different time points (1, 6, 12 h) in all the three NPC cell lines (Figure 7A), while knockdown of MAPK15 led to higher ROS accumulation compared to the NT control in the irradiated CNE2-IR cells (Figure 7B). This evidence concerns the gene MAPK15 and nasopharyngeal carcinoma.