SIRT6 and ovarian carcinoma: In 104 ovarian carcinomas, the factors significantly associated with both OS and RFS in univariate analysis were age of patients, tumor stage, presence of ascites, serum level of CA125, histologic grade, and the expression of Nu-SIRT6, Nu-Aβ-catenin, and Cy-Aβ-catenin (Table 3) (Figure 2).