TNKS2 and neoplasm: In particular, compared to the vector control, CRL1623‐IL‐18‐injected tumor xenografts expressed high levels of IL‐18 (P < 0.01), β‐catenin (P = 0.028), TNKS2 (P = 0.045), and N‐cadherin (P = 0.068), but lower levels of E‐cadherin (P = 0.045), and thus the E/N ratio was changed (Table 4).