BRCA1 and breast cancer: Previous studies have demonstrated the interaction between ZBRK1 and the breast and ovarian cancer susceptibility protein 1 (BRCA1) breast cancer molecule in the transcriptional regulation of many BRCA1 target genes, including growth arrest and DNA‐damage‐inducible 45 alpha (GADD45α), a protein involved in cell cycle control and DNA damage response 7, 8, angiopoietin‐1 (ANG1) 9, 10, and high‐mobility group AT‐hook 2 (HMGA2) 11, 12, 13.