The prevalences of pulmonary embolism (46.7 vs. 16.7%; p = 0.022) and catastrophic APS (20 vs. 2.4%; p = 0.023) were significantly higher in patients with triple aPL positivity than in individuals with single or double aPL positivity (Table 3). This evidence concerns the gene FASLG and autoimmune polyendocrinopathy.